The only supplement I have taken is protein powder. I take a serving (which is ~45g of protein, I think) immediately after strength training workouts (i.e. lifting weights - not after running, biking, hiking, etc). I usually lift 4 days per week, so 4 servings of protein powder a week. I also try to drink a lot of water on days I know I will be taking it....so that is what I do. I am a bigger guy as well (6'1" 225 lbs) and also get a lot of protein from other places but like to make sure I get enough on lifting days. Will I continue this forever? No...but right now, I am really trying to build muscle....once I am happier with where I am, I think diet and continuing to work out should do the job just fine. So, I guess what I am saying is yeah, I take the protein powder....but its in limited quantity, I don't plan on doing it long term, and I don't think that its absolutely necessary by any means.
As for the infusion sets, I have had the same problem. Even though my insurance pays for them, nothing makes me more angry than when one falls off or gets yanked out before I am done with it....I just hate to waste them. So here are my tricks that I use... If I really want it to stick good, I will shave the hair off at the site before inserting. Just seems to get a better "bite" when you stick it down....also seems more sanitary for some reason. Plus, I almost always insert in my thighs and I am pretty sure that I don't need thigh-hair anyway. Then I use IV prep....let it dry until its sticky and then insert. That will usually hold for a couple days with no problems.
Once the infusion set adhesive starts to loosen from working out, sweat, getting yanked on, etc. I will disconnect my pump at the infusion site, then take one of the IV 3000 Transparent Dressings and before peeling it off to stick down, I cut a hole large enough to go around the plastic part of the infusion set still in my body. Then I stick it down so that it covers the old adhesive on the infusion set and surrounding skin, but the portion that connects back to my pump sticks up thru the hole....then reconnect and it usually holds up for as long as I need it to. I don't do this right away simply because I want to save the IV 3000 Dressings until I actually end up needing them... I have also tried sticking the IV 3000 down first and then inserting the infusion set right thru it, but it only held marginally better and I would have to use the IV 3000 every time.
So that is what I do and it seems to work pretty well, actually. Oh, and I use the Soft-Set infusion sets....I'd imagine the same thing would work with the Silhouettes if you cut the hole large enough... To cut the hole, I just don't peel off the back, loosely fold the thing in half, and just snip a big chunk out of the middle of the fold with some scissors....easy enough.
Anyway, hope that helps. Let me know if you have any other questions.